概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      NLSSEDPNLFGSNSLDGGSSPMIKPKGDKQVEYLDLDLDSGKSTPPRKQK SSGSGSSVADERVDYVVVDQQKTLALKSTREAWTDGRQSTESETPPKSVK
    • 分子量
      37 kDa including tags
    • 氨基酸
      625 to 724

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技术指标

Our Abpromise guarantee covers the use of ab152405 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    ELISA

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Gab 1
    • GAB1
    • GAB1_HUMAN
    • GRB 2 associated binder 1
    • GRB 2 associated binding protein 1
    • GRB2 associated binding protein 1 isoform a
    • GRB2 associated binding protein 1 isoform b
    • GRB2-associated binder 1
    • GRB2-associated-binding protein 1
    • Growth factor receptor bound protein 2-associated protein 1
    see all
  • 功能
    Probably involved in EGF and insulin receptor signaling.
  • 序列相似性
    Belongs to the GAB family.
    Contains 1 PH domain.
  • 翻译后修饰
    Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE analysis of ab152405 stained with Coomassie Blue.

文献

ab152405 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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