Recombinant人FVT1 protein (ab125172)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ06136
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MKPLALPGAH VVVTGGSSGI GKCIAIECYK QGAFITLVAR NEDKLLQAKK EIEMHSINDK QVVLCISVDV SQDYNQVENV IKQAQEKLGP VDMLVNCAGM AVSGKFEDLE VSTFERLMSI NYLGSVYPSR AVITTMKERR VGRIVFVSSQ AGQLGLFGFT AYSASKFAIR GLAEALQMEV KPYNVYITVA YPPDTDTPGF AEENRTKPLE TRLISETTSV CKPEQVAKQI VKDAIQGNFN SSLGSD
    • 分子量29 kDa including tags
    • 氨基酸26 to 270
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab125172 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    ab125172 is purified by proprietary chromatographic techniques.
  • 形式Liquid
  • 补充说明ab125172 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Store under Desiccating conditions.

    pH: 8.00
    Constituents: 0.002% PMSF, 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride

常规信息

  • 别名
    • 3 dehydrosphinganine reductase
    • 3 ketodihydrosphingosine reductase
    • 3-dehydrosphinganine reductase
    • 3-ketodihydrosphingosine reductase
    • DHSR
    • FLJ36555
    • FLJ92680
    • Follicular lymphoma variant translocation 1
    • Follicular variant translocation protein 1
    • FVT 1
    • FVT-1
    • FVT1
    • KDS reductase
    • KDSR
    • KDSR_HUMAN
    • SDR35C1
    • Short chain dehydrogenase/reductase family 35C member 1
    see all
  • 功能Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
  • 组织特异性Expressed in all tissues examined. Highest expression in placenta. High expression in lung, kidney, stomach and small intestine, low expression in heart, spleen and skeletal muscle. Weakly expressed in normal hematopoietic tissues. Higher expression in some T-cell malignancies and PHA-stimulated lymphocytes.
  • 通路Lipid metabolism; sphingolipid metabolism.
  • 疾病相关A chromosomal aberration involving KDSR is a cause of follicular lymphoma; also known as type II chronic lymphatic leukemia. Translocation t(2;18)(p11;q21) with a Ig J kappa chain region (PubMed:8417785).
  • 序列相似性Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • 细胞定位Endoplasmic reticulum membrane.
  • Information by UniProt

Recombinant Human FVT1 protein (ab125172)参考文献

ab125172 has not yet been referenced specifically in any publications.

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