Recombinant人FVT1 protein (ab104822)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHHSSGLVPRGSHMKPLALPGAHVVVTGGSSGIGKCIAIECYK QGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENV IKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSR AVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEV KPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISETTSVCKPEQVAKQI VKDAIQGNFNSSLGSD
    • 分子量
      29 kDa including tags
    • 氨基酸
      26 to 270
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab104822 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度
    > 90 % SDS-PAGE.
    ab104822 was purified using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, 0.1mM PMSF, pH 8.0

常规信息

  • 别名
    • 3 dehydrosphinganine reductase
    • 3 ketodihydrosphingosine reductase
    • 3-dehydrosphinganine reductase
    • 3-ketodihydrosphingosine reductase
    • DHSR
    • FLJ36555
    • FLJ92680
    • Follicular lymphoma variant translocation 1
    • Follicular variant translocation protein 1
    • FVT 1
    • FVT-1
    • FVT1
    • KDS reductase
    • KDSR
    • KDSR_HUMAN
    • SDR35C1
    • Short chain dehydrogenase/reductase family 35C member 1
    see all
  • 功能
    Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
  • 组织特异性
    Expressed in all tissues examined. Highest expression in placenta. High expression in lung, kidney, stomach and small intestine, low expression in heart, spleen and skeletal muscle. Weakly expressed in normal hematopoietic tissues. Higher expression in some T-cell malignancies and PHA-stimulated lymphocytes.
  • 通路
    Lipid metabolism; sphingolipid metabolism.
  • 疾病相关
    A chromosomal aberration involving KDSR is a cause of follicular lymphoma; also known as type II chronic lymphatic leukemia. Translocation t(2;18)(p11;q21) with a Ig J kappa chain region (PubMed:8417785).
  • 序列相似性
    Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • 细胞定位
    Endoplasmic reticulum membrane.
  • Information by UniProt

Recombinant Human FVT1 protein 图像

  • 15% SDS-PAGE analysis of 3µg ab104822.

Recombinant Human FVT1 protein (ab104822)参考文献

ab104822 has not yet been referenced specifically in any publications.

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