概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      HEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGA QVIQMLAQNYRLPQPSNCPQQFYNIMLECWNAEPKERPTFETLRWKLEDY FETDSSYSDANNFIR
    • 分子量
      38 kDa including tags
    • 氨基酸
      391 to 505

技术指标

Our Abpromise guarantee covers the use of ab152399 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

    ELISA

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Beta cell Src homology tyrosine kinase
    • BSK
    • BSK/IYK
    • C85044
    • Frk
    • Frk fyn related kinase
    • FRK_HUMAN
    • FYN related kinase
    • FYN-related kinase
    • GASK
    • Gastrointestinal associated kinase
    • Gastrointestinal associated tyrosine kinase
    • GTK
    • GTK, mouse, homolog of
    • Intestine tyrosine kinase
    • Nuclear tyrosine protein kinase RAK
    • Protein-tyrosine kinase 5
    • PTK5
    • PTK5 protein tyrosine kinase 5
    • RAK
    • Tyrosine protein kinase FRK
    • Tyrosine-protein kinase FRK
    see all
  • 功能
    Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
  • 组织特异性
    Restricted to cells lines derived from tissues of lymphoid, brain, breast, colon and bladder origin.
  • 序列相似性
    Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH2 domain.
    Contains 1 SH3 domain.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE analysis of ab152399 stained with Coomassie Blue.

文献

ab152399 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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