Recombinant人FPRL1 protein (ab114357)

概述

  • 产品名称
    Recombinant人FPRL1 protein
  • 蛋白长度
    Protein fragment

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      FLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIR
    • 分子量
      30 kDa including tags
    • 氨基酸
      163 to 205

技术指标

Our Abpromise guarantee covers the use of ab114357 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • ALXR
    • FMLP-R-I
    • FMLP-R-II
    • FMLP-related receptor I
    • FMLPX
    • Formyl peptide receptor 2
    • Formyl peptide receptor related
    • Formyl peptide receptor-like 1
    • FPR2
    • FPR2_HUMAN
    • FPR2A
    • FPRH1
    • FPRH2
    • FPRL1
    • HM63
    • Lipoxin A4 receptor
    • LXA4 receptor
    • LXA4R
    • N-formyl peptide receptor 2
    • RFP
    see all
  • 功能
    Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
  • 组织特异性
    Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis.
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位
    Cell membrane.
  • Information by UniProt

图片

  • ab114357 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

文献

ab114357 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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