Our Abpromise guarantee covers the use of ab90416 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Functional Studies
SDS-PAGE
Human FPR1 exists in various isoforms, FPR-26, FPR-98 and FPR-G6, respectively. These FPR isoforms differ from each other in amino acid positions 101 (localized at the top of the third transmembrane domain), 192 (localized in the center of the second extracellular loop) and 346 (localized at the extreme C-terminus). (FPR-26: V101, N192, E346; FPR-98: L101, N192, A346; FPR-G6: V101, K192, A346). ab90416 (FPR-98) exhibits a partial Gi-protein coupling defect relative to FPR-26.
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Preservative: None
Constituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4
ab90416 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"