Recombinant人FOXG1 protein (ab114230)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      SPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSSVLTQNSLGNNHSFSTAN GLSVDRLVNGE
    • 分子量
      32 kDa including tags
    • 氨基酸
      164 to 224

技术指标

Our Abpromise guarantee covers the use of ab114230 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • BF-1
    • BF-2
    • BF1
    • BF2
    • Brain factor 1
    • Brain factor 2
    • FHKL
    • FKH2
    • FKHL1
    • FKHL2
    • FKHL3
    • FKHL4
    • Forkhead box protein G1
    • Forkhead box protein G1A
    • Forkhead box protein G1B
    • Forkhead box protein G1C
    • Forkhead like 1
    • Forkhead like 2
    • Forkhead like 3
    • Forkhead like 4
    • Forkhead-related protein FKHL1
    • Forkhead-related protein FKHL2
    • Forkhead-related protein FKHL3
    • FOXG1
    • FOXG1_HUMAN
    • FOXG1A
    • FOXG1B
    • FOXG1C
    • HBF 1
    • HBF G2
    • hBF-2
    • HBF2
    • HFK1
    • HFK2
    • HFK3
    • KHL2
    • Oncogene QIN
    • QIN
    see all
  • 功能
    Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.
  • 组织特异性
    Expression is restricted to the neurons of the developing telencephalon.
  • 疾病相关
    Defects in FOXG1 are the cause of congenital variant of Rett syndrome (RTTCV) [MIM:613454]. RTTCV is a severe neurodevelopmental disorder with features of classic Rett syndrome but earlier onset in the first months of life. Clinical features include progressive microcephaly, hypotonia, irresponsiveness and irritability in the neonatal period, mental retardation, psychomotor regression and stereotypical movements.
  • 序列相似性
    Contains 1 fork-head DNA-binding domain.
  • 细胞定位
    Nucleus.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE showing ab114230 at approximately 32.24kDa stained with Coomassie Blue.

文献

ab114230 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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