Recombinant人FKBP6 protein (ab123536)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionO75344
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MGGSALNQGV LEGDDAPGQS LYERLSQRML DISGDRGVLK DVIREGAGDL VAPDASVLVK YSGYLEHMDR PFDSNYFRKT PRLMKLGEDI TLWGMELGLL SMRRGELARF LFKPNYAYGT LGCPPLIPPN TTVLFEIELL DFLDCAESDK FCALSAEQQD QFPLQKVLKV AATEREFGNY LFRQNRFYDA KVRYKRALLL LRRRSAPPEE QHLVEAAKLP VLLNLSFTYL KLDRPTIALC YGEQALIIDQ KNAKALFRCG QACLLLTEYQ KARDFLVRAQ KEQPFNHDIN NELKKLASCY RDYVDKEKEM WHRMFAPCGD GSTAGES.
    • 分子量39 kDa including tags
    • 氨基酸1 to 327
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab123536 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Specific activity is > 50 nmoles/min/ug, and is defined as the amount of enzyme that cleaves 1umole of suc-AAFP-pNA per minute at 1C in Tris-Hcl pH8.0 using chymotrypsin.
  • 应用

    Functional Studies

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab123536 was purified by standard chromatography and filter sterilized.
  • 形式Liquid
  • 补充说明Please prevent freeze thaw cycles.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Store under Desiccating conditions.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 0.03% EDTA, 40% Glycerol, 0.29% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • 36 kDa FK506 binding protein
    • 36 kDa FK506-binding protein
    • 36 kDa FKBP
    • EC 5.2.1.8
    • FK506 binding protein 6
    • FK506-binding protein 6
    • FKBP 36
    • FKBP-36
    • FKBP-6
    • FKBP36
    • fkbp6
    • FKBP6_HUMAN
    • Immunophilin FKBP36
    • Peptidyl prolyl cis trans isomerase
    • Peptidyl-prolyl cis-trans isomerase FKBP6
    • PPIase
    • PPIase FKBP6
    • Rotamase
    see all
  • 功能PPIases accelerate the folding of proteins.
  • 组织特异性Detected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver, and kidney.
  • 疾病相关Note=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
  • 序列相似性Contains 1 PPIase FKBP-type domain.
    Contains 3 TPR repeats.
  • Information by UniProt

Recombinant human FKBP6 protein (ab123536)参考文献

ab123536 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab123536.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"