Recombinant人Fetuin A protein (ab123466)

概述

描述

  • 性质
    Recombinant
  • 来源
    HEK 293 cells
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      APHGPGLIYR QPNCDDPETE EAALVAIDYI NQNLPWGYKH TLNQIDEVKV WPQQPSGELF EIEIDTLETT CHVLDPTPVA RCSVRQLKEH AVEGDCDFQL LKLDGKFSVV YAKCDSSPDS AEDVRKVCQD CPLLAPLNDT RVVHAAKAAL AAFNAQNNGS NFQLEEISRA QLVPLPPSTY VEFTVSGTDC VAKEATEAAK CNLLAEKQYG FCKATLSEKL GGAEVAVTCT VFQTQPVTSQ PQPEGANEAV PTPVVDPDAP PSPPLGAPGL PPAGSPPDSH VLTVVQPSVG AAAGPVVPPC PGRIRHFKV

技术指标

Our Abpromise guarantee covers the use of ab123466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    Biological Activity: Determined by its ability to inhibit Cathespin V cleavage of a fluorogenic peptide substrate Z-LR-AMC (RLUs). The expected IC50 is = 100nM.
  • 应用

    Functional Studies

    HPLC

    SDS-PAGE

  • 内毒素水平
    < 0.100 Eu/µg
  • 纯度
    > 98 % SDS-PAGE.
    Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.
  • 形式
    Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • 59 kDa bone sialic acid containing protein
    • A2HS
    • Aa2 066
    • AHS
    • Ahsg
    • Alpha 2 HS glycoprotein
    • Alpha 2 HS glycoprotein chain A
    • Alpha 2 HS glycoprotein chain B
    • Alpha 2 Z globulin
    • Alpha 2HS glycoprotein
    • Alpha-2-HS-glycoprotein chain B
    • Alpha-2-Z-globulin
    • alpha2 Heremans Schmid glycoprotein
    • Asialofetuin
    • Ba alpha 2 glycoprotein
    • Ba-alpha-2-glycoprotein
    • BSP
    • Countertrypin
    • FETUA
    • FETUA_HUMAN
    • Fetuin A
    • Fetuin, mouse, homolog of
    • Fetuin-A
    • FetuinA
    • Glycoprotein PP63
    • HSGA
    • pp63
    see all
  • 功能
    Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.
  • 组织特异性
    Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.
  • 序列相似性
    Belongs to the fetuin family.
    Contains 2 cystatin fetuin-A-type domains.
  • 翻译后修饰
    Phosphorylation sites are present in the extracelllular medium.
  • 细胞定位
    Secreted.
  • Information by UniProt

文献

ab123466 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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