Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuratus)
Fascin, sea urchin, homolog of, 1
Singed (Drosophila) like (sea urchin fascin homolog like)
Singed drosophila homolog like
Singed like (fascin homolog sea urchin)
Singed like (fascin homolog sea urchin) (Drosophila)
Singed like protein
Singed, drosophila, homolog of
功能Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
序列相似性Belongs to the fascin family.
结构域Composed of four beta-trefoil domains.
翻译后修饰Phosphorylation on Ser-39 inhibits the actin-binding ability of fascin.