Recombinant人Fascin protein (ab99240)

概述

  • 产品名称Recombinant人Fascin protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ16658
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MTANGTAEAV QIQFGLINCG NKYLTAEAFG FKVNASASSL KKKQIWTLEQ PPDEAGSAAV CLRSHLGRYL AADKDGNVTC EREVPGPDCR FLIVAHDDGR WSLQSEAHRR YFGGTEDRLS CFAQTVSPAE KWSVHIAMHP QVNIYSVTRK RYAHLSARPA DEIAVDRDVP WGVDSLITLA FQDQRYSVQT ADHRFLRHDG RLVARPEPAT GYTLEFRSGK VAFRDCEGRY LAPSGPSGTL KAGKATKVGK DELFALEQSC AQVVLQAANE RNVSTRQGMD LSANQDEETD QETFQLEIDR DTKKCAFRTH TGKYWTLTAT GGVQSTASSK NASCYFDIEW RDRRITLRAS NGKFVTSKKN GQLAASVETA GDSELFLMKL INRPIIVFRG EHGFIGCRKV TGTLDANRSS YDVFQLEFND GAYNIKDSTG KYWTVGSDSA VTSSGDTPVD FFFEFCDYNK VAIKVGGRYL KGDHAGVLKA SAETVDPASL WEY
    • 分子量57 kDa including tags
    • 氨基酸1 to 493
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab99240 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab99240 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 2mM DTT, 100mM Sodium chloride, pH 8.0

常规信息

  • 别名
    • 55 kDa actin bundling protein
    • 55 kDa actin-bundling protein
    • Actin bundling protein
    • actin bundling protein, 55-KD
    • FAN 1
    • FAN1
    • Fascin
    • Fascin 1
    • Fascin actin bundling protein 1
    • Fascin homolog 1
    • Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuratus)
    • Fascin, sea urchin, homolog of, 1
    • Fascin1
    • FLJ38511
    • FSCN 1
    • FSCN1
    • FSCN1_HUMAN
    • HSN
    • p55
    • Singed (Drosophila) like (sea urchin fascin homolog like)
    • Singed drosophila homolog like
    • Singed like (fascin homolog sea urchin)
    • Singed like (fascin homolog sea urchin) (Drosophila)
    • Singed like protein
    • Singed, drosophila, homolog of
    • Singed-like protein
    • SNL
    • Strongylocentrotus purpuratus
    see all
  • 功能Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
  • 组织特异性Ubiquitous.
  • 序列相似性Belongs to the fascin family.
  • 结构域Composed of four beta-trefoil domains.
  • 翻译后修饰Phosphorylation on Ser-39 inhibits the actin-binding ability of fascin.
  • 细胞定位Cytoplasm > cytoskeleton. Cell projection > filopodium. Cell projection > invadopodium.
  • Information by UniProt

Recombinant Human Fascin protein 图像

  • 15% SDS-PAGE showing ab99240 at approximately 56.7kDa (3µg).

Recombinant Human Fascin protein (ab99240)参考文献

ab99240 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"