The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
补充说明Protein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.79% Tris HCl, 0.3% Glutathione
DNA repair protein XRCC9
Fanconi anaemia complementation group G
Fanconi anemia group G protein
X ray repair, complementing defective, in Chinese hamster cells 9
X-ray repair, complementing defective, in Chinese hamster, 9
功能DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.
组织特异性Highly expressed in testis and thymus. Found in lymphoblasts.
疾病相关Defects in FANCG are a cause of Fanconi anemia (FA) [MIM:227650]. FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.
序列相似性Contains 4 TPR repeats.
细胞定位Nucleus. Cytoplasm. The major form is nuclear. The minor form is cytoplasmic.