Recombinant人FANCF protein (ab116744)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ9NPI8
    • 种属Human
    • 序列MESLLQHLDRFSELLAVSSTTYVSTWDPATVRRALQWARYLRHIHRRFGR HGPIRTALERRLHNQWRQEGGFGRGPVPGLANFQALGHCDV
    • 分子量36 kDa including tags
    • 氨基酸1 to 91

技术指标

Our Abpromise guarantee covers the use of ab116744 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    Western blot

    SDS-PAGE

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

常规信息

  • 别名
    • A730016A17
    • FACF
    • FAF
    • FANCF
    • FANCF_HUMAN
    • Fanconi anemia complementation group F
    • Fanconi anemia group F protein
    • MGC126856
    • Protein FACF
    • RGD1561456
    see all
  • 功能DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
  • 疾病相关Defects in FANCF are a cause of Fanconi anemia (FA) [MIM:227650]. FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human FANCF protein 图像

  • 12.5% SDS-PAGE of ab116744 at approximately 35.64kDa stained with Coomassie Blue.

Recombinant Human FANCF protein (ab116744)参考文献

ab116744 has not yet been referenced specifically in any publications.

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