概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MAPDPVAAETAAQGPTPRYFTWDEVAQRSGCEERWLVIDRKVYNISEFTR RHPGGSRVISHYAGQDATDPFVAFHINKGLVKKYMNSLLIGELSPEQPSF EPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLTL WVFGTSFLPFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFV IGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINMHPFFFALGKILSVELG KQKKKYMPYNHQHKYFFLIGPSALLPLYFQWYIFYFVIQRKKWVDLAWMI TFYVRFFLTYVPLLGLKAFLGLFFIVRFLESNWFVWVTQMNHIPMHIDHD RNMDWVSTQLQATCNVHKSAFNDWFSGHLNFQIEHHLFPTMPRHNYHKVA PLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ
    • 分子量
      74 kDa including tags
    • 氨基酸
      1 to 444

技术指标

Our Abpromise guarantee covers the use of ab152502 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    ELISA

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • D5D
    • Delta 5 desaturase
    • Delta 5 fatty acid desaturase
    • Delta(5) desaturase
    • Delta(5) fatty acid desaturase
    • Delta-5 desaturase
    • Fads1
    • FADS1_HUMAN
    • FADS6
    • FADSD5
    • Fatty acid desaturase 1
    • FLJ38956
    • Linoleoyl CoA desaturase (delta 6 desaturase) like 1
    • LLCDL1
    • TU12
    see all
  • 功能
    Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3) respectively.
  • 组织特异性
    Expressed in many tissues, it is most abundant in the liver, brain, adrenal gland and heart. Found as well in skeletal muscle, lung, placenta, kidney, pancreas and retina.
  • 通路
    Lipid metabolism; polyunsaturated fatty acid biosynthesis.
  • 序列相似性
    Belongs to the fatty acid desaturase family.
    Contains 1 cytochrome b5 heme-binding domain.
  • 发展阶段
    Highly expressed in fetal liver and fetal brain.
  • 结构域
    The histidine box domains may contain the active site and/or be involved in metal ion binding.
  • 细胞定位
    Endoplasmic reticulum membrane.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE analysis of ab152502 stained with Coomassie Blue.

文献

ab152502 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab152502.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册