Recombinant人FADD protein (ab89242)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab89242 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab89242 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, pH 8.0

常规信息

  • 别名
    • FADD
    • FADD protein
    • FADD_HUMAN
    • Fas (TNFRSF6) associated via death domain
    • Fas associated via death domain
    • Fas associating death domain containing protein
    • Fas associating protein
    • Fas associating protein with death domain
    • Fas TNFRSF6 associated via death domain
    • FAS-associated death domain protein
    • FAS-associating death domain-containing protein
    • GIG 3
    • GIG3
    • Growth inhibiting gene 3 protein
    • Growth-inhibiting gene 3 protein
    • H sapiens mRNA for mediator of receptor induced toxicity
    • Mediator of receptor induced toxicity
    • MGC8528
    • MORT 1
    • MORT1
    • Protein FADD
    see all
  • 功能Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
  • 组织特异性Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes.
  • 序列相似性Contains 1 death domain.
    Contains 1 DED (death effector) domain.
  • 结构域Contains a death domain involved in the binding of the corresponding domain within Fas receptor.
  • Information by UniProt

Recombinant Human FADD protein 图像

  • 15% SDS-PAGE showing ab89242 at approximately 27.4kDa (3µg).

Recombinant Human FADD protein (ab89242)参考文献

ab89242 has not yet been referenced specifically in any publications.

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