Recombinant人FABP6 protein (ab87381)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • 种属
      Human
    • 序列
      MAFTGKFEME SEKNYDEFMK LLGISSDVIE KAHNFKIVTE VQQDGQDFTW SQHYYGGHTM TNKFTVGKES NIQTMGGKTF KATVQMEGGK LVVNFPNYHQ TSEIVGDKLV EVSTIGGVTY ERVSKRLA

技术指标

Our Abpromise guarantee covers the use of ab87381 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    ab87381 corresponds to isoform 2, 128 aas.
  • 应用

    SDS-PAGE

  • 纯度
    > 95 % SDS-PAGE.
    Purified by using conventional chromatography techniques.
  • 形式
    Liquid
  • 补充说明
    ab87381 corresponds to isoform 2, 128 aas.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C.

    Preservative: None
    Constituents: 10% Glycerol, PBS, pH 7.4

常规信息

  • 别名
    • Fabp6
    • FABP6_HUMAN
    • Fatty acid binding protein 6, ileal (gastrotropin)
    • Fatty acid-binding protein 6
    • Gastrotropin
    • GT
    • I 15P
    • I BABP
    • I BALB
    • I BAP
    • I-15P
    • I-BABP
    • I15P
    • IBABP
    • IBALB
    • IBAP
    • ILBP
    • ILBP3
    • Ileal lipid binding protein
    • Ileal lipid-binding protein
    • ILLBP
    • Intestinal 15 kDa protein
    • Intestinal bile acid binding protein
    • Intestinal bile acid-binding protein
    see all
  • 功能
    Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.
  • 组织特异性
    Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum.
  • 序列相似性
    Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
  • 结构域
    Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.
  • 细胞定位
    Cytoplasm and Cytoplasm. Localized close to nucleus on the apical side of both normal and neoplastic cells.
  • Information by UniProt

Recombinant Human FABP6 protein 图像

  • ab87381 on 15% SDS-PAGE (3µg)

Recombinant Human FABP6 protein (ab87381)参考文献

ab87381 has not yet been referenced specifically in any publications.

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