Recombinant人FABP6 protein (ab87381)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列MAFTGKFEME SEKNYDEFMK LLGISSDVIE KAHNFKIVTE VQQDGQDFTW SQHYYGGHTM TNKFTVGKES NIQTMGGKTF KATVQMEGGK LVVNFPNYHQ TSEIVGDKLV EVSTIGGVTY ERVSKRLA

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技术指标

Our Abpromise guarantee covers the use of ab87381 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性ab87381 corresponds to isoform 2, 128 aas.
  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    Purified by using conventional chromatography techniques.
  • 形式Liquid
  • 补充说明ab87381 corresponds to isoform 2, 128 aas.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C.

    Preservative: None
    Constituents: 10% Glycerol, PBS, pH 7.4

常规信息

  • 别名
    • Fabp6
    • FABP6_HUMAN
    • Fatty acid binding protein 6, ileal (gastrotropin)
    • Fatty acid-binding protein 6
    • Gastrotropin
    • GT
    • I 15P
    • I BABP
    • I BALB
    • I BAP
    • I-15P
    • I-BABP
    • I15P
    • IBABP
    • IBALB
    • IBAP
    • ILBP
    • ILBP3
    • Ileal lipid binding protein
    • Ileal lipid-binding protein
    • ILLBP
    • Intestinal 15 kDa protein
    • Intestinal bile acid binding protein
    • Intestinal bile acid-binding protein
    see all
  • 功能Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.
  • 组织特异性Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum.
  • 序列相似性Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
  • 结构域Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.
  • 细胞定位Cytoplasm and Cytoplasm. Localized close to nucleus on the apical side of both normal and neoplastic cells.
  • Information by UniProt

Recombinant Human FABP6 protein 图像

  • ab87381 on 15% SDS-PAGE (3µg)

Recombinant Human FABP6 protein (ab87381)参考文献

ab87381 has not yet been referenced specifically in any publications.

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