Recombinant人FABP6 protein (ab113855)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP51161
    • 种属Human
    • 序列MKHHHHHHAS AFTGKFEMES EKNYDEFMKL LGISSDVIEK ARNFKIVTEV QQDGQDFTWS QHYSGGHTMT NKFTVGKESN IQTMGGKTFK ATVQMEGGKL VVNFPNYHQT SEIVGDKLVE VSTIGGVTYE RVSKRLA
    • 分子量16 kDa including tags
    • 氨基酸2 to 128
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab113855 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

    ELISA

  • 内毒素水平< 1.000 Eu/µg
  • 纯度> 95 % Densitometry.

  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.40
    Constituents: 99% Phosphate Buffer, 0.44% Sodium chloride

  • 复溶Add deionized water (200 µl) to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

常规信息

  • 别名
    • Fabp6
    • FABP6_HUMAN
    • Fatty acid binding protein 6, ileal (gastrotropin)
    • Fatty acid-binding protein 6
    • Gastrotropin
    • GT
    • I 15P
    • I BABP
    • I BALB
    • I BAP
    • I-15P
    • I-BABP
    • I15P
    • IBABP
    • IBALB
    • IBAP
    • ILBP
    • ILBP3
    • Ileal lipid binding protein
    • Ileal lipid-binding protein
    • ILLBP
    • Intestinal 15 kDa protein
    • Intestinal bile acid binding protein
    • Intestinal bile acid-binding protein
    see all
  • 功能Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.
  • 组织特异性Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum.
  • 序列相似性Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
  • 结构域Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.
  • 细胞定位Cytoplasm and Cytoplasm. Localized close to nucleus on the apical side of both normal and neoplastic cells.
  • Information by UniProt

Recombinant Human FABP6 protein 图像

  • 14% SDS-PAGE
    Lane 1: reduced and heated FABP6, 5µg/lane
    Lane 2. non-reduced and non-heated FABP6, 5µg/lane

Recombinant Human FABP6 protein (ab113855)参考文献

ab113855 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"