Recombinant人Estrogen Inducible Protein pS2 (ab89485)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列MKHHHHHHAS EAQTETCTVA PRERQNCGFP GVTPSQCANK GCCFDDTVRG VPWCFYPNTI DVPPEEECEF

技术指标

Our Abpromise guarantee covers the use of ab89485 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

    ELISA

  • 纯度> 95 % SDS-PAGE.

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20mM Sodium chloride, 20mM Tris, pH 7.5

常规信息

  • 别名
    • BCEI
    • Breast cancer estrogen inducible protein
    • Breast cancer estrogen inducible sequence
    • Breast cancer estrogen-inducible protein
    • D21S21
    • Gastrointestinal trefoil protein
    • Gastrointestinal trefoil protein pS2
    • hP1.A
    • HP1A
    • HPS 2
    • HPS2
    • pNR 2
    • PNR-2
    • pNR2
    • Polypeptide P1.A
    • Protein pS2
    • PS 2
    • pS2
    • pS2 protein
    • TFF 1
    • TFF1
    • TFF1_HUMAN
    • Trefoil factor 1
    see all
  • 功能Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.
  • 组织特异性Found in stomach, with highest levels in the upper gastric mucosal cells (at protein level). Detected in goblet cells of the small and large intestine and rectum, small submucosal glands in the esophagus, mucous acini of the sublingual gland, submucosal glands of the trachea, and epithelial cells lining the exocrine pancreatic ducts but not in the remainder of the pancreas (at protein level). Scattered expression is detected in the epithelial cells of the gallbladder and submucosal glands of the vagina, and weak expression is observed in the bronchial goblet cells of the pseudostratified epithelia in the respiratory system (at protein level). Detected in urine (at protein level). Strongly expressed in breast cancer but at low levels in normal mammary tissue. It is regulated by estrogen in MCF-7 cells. Strong expression found in normal gastric mucosa and in the regenerative tissues surrounding ulcerous lesions of gastrointestinal tract, but lower expression found in gastric cancer (at protein level).
  • 序列相似性Contains 1 P-type (trefoil) domain.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant Human Estrogen Inducible Protein pS2 图像

  • 12% SDS-PAGE separation of ab89485
    1. MWt marker – 14, 21, 31, 45, 66, 97 kDa
    2. reduced and heated sample, 5µg/lane
    3. non-reduced and non-heated sample, 5µg/lane

Recombinant Human Estrogen Inducible Protein pS2 (ab89485)参考文献

ab89485 has not yet been referenced specifically in any publications.

Product Wall

Thanks for your inquiry. The estrogen inducible protein (ab89485) was expressed as a fusion protein with N-terminal his-tag composed of 10 amino acids. The first 10 amino acids in the protein sequence belong to the his-tag. The rest of the amino...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"