Recombinant人Estrogen Inducible Protein pS2 (ab51744)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab51744 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    >98% by SDS-PAGE and HPLC analyses. Endotoxin level is <0.1 ng per µg of Human TFF1. Sterile filtered.
  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

  • 复溶Lyophilized without additives. Reconstitute in water to a concentration of 0.1-1.0 mg/ml.

常规信息

  • 别名
    • BCEI
    • Breast cancer estrogen inducible protein
    • Breast cancer estrogen inducible sequence
    • Breast cancer estrogen-inducible protein
    • D21S21
    • Gastrointestinal trefoil protein
    • Gastrointestinal trefoil protein pS2
    • hP1.A
    • HP1A
    • HPS 2
    • HPS2
    • pNR 2
    • PNR-2
    • pNR2
    • Polypeptide P1.A
    • Protein pS2
    • PS 2
    • pS2
    • pS2 protein
    • TFF 1
    • TFF1
    • TFF1_HUMAN
    • Trefoil factor 1
    see all
  • 功能Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.
  • 组织特异性Found in stomach, with highest levels in the upper gastric mucosal cells (at protein level). Detected in goblet cells of the small and large intestine and rectum, small submucosal glands in the esophagus, mucous acini of the sublingual gland, submucosal glands of the trachea, and epithelial cells lining the exocrine pancreatic ducts but not in the remainder of the pancreas (at protein level). Scattered expression is detected in the epithelial cells of the gallbladder and submucosal glands of the vagina, and weak expression is observed in the bronchial goblet cells of the pseudostratified epithelia in the respiratory system (at protein level). Detected in urine (at protein level). Strongly expressed in breast cancer but at low levels in normal mammary tissue. It is regulated by estrogen in MCF-7 cells. Strong expression found in normal gastric mucosa and in the regenerative tissues surrounding ulcerous lesions of gastrointestinal tract, but lower expression found in gastric cancer (at protein level).
  • 序列相似性Contains 1 P-type (trefoil) domain.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant Human Estrogen Inducible Protein pS2 (ab51744)参考文献

ab51744 has not yet been referenced specifically in any publications.

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