Recombinant人ER81 protein (ab112285)

概述

  • 产品名称
    Recombinant人ER81 protein
  • 蛋白长度
    Protein fragment

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      LHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSF PPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAAS QSFPPPLMIK
    • 分子量
      38 kDa including tags
    • 氨基酸
      148 to 257
    • 标签
      GST tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab112285 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    ELISA

    SDS-PAGE

  • 形式
    Liquid
  • 补充说明
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione

常规信息

  • 别名
    • DKFZp781L0674
    • ER81
    • ER81 protein
    • ER81, mouse, homolog of
    • ETS translocation variant 1
    • ets variant gene 1
    • Ets-related protein 81
    • Etsrp81
    • ETV 1
    • ETV1
    • ETV1_HUMAN
    • MGC104699
    • MGC120533
    • MGC120534
    see all
  • 功能
    Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
  • 组织特异性
    Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes.
  • 疾病相关
    Defects in ETV1 are a cause of Ewing sarcoma (ES) [MIM:612219]. A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors. Note=A chromosomal aberration involving ETV1 is found in patients with Erwing sarcoma. Translocation t(7;22)(p22;q12) with EWSR1.
  • 序列相似性
    Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
  • 翻译后修饰
    Sumoylated.
  • 细胞定位
    Nucleus.
  • Information by UniProt

Recombinant Human ER81 protein 图像

  • ab112285 analysis using 12.5% SDS-PAGE Stained with Coomassie Blue

Recombinant Human ER81 protein (ab112285)参考文献

ab112285 has not yet been referenced specifically in any publications.

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