Recombinant人Epoxide hydrolase protein (ab114694)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MWLEILLTSVLGFAIYWFISRDKEETLPLEDGWWGPGTRSAAREDDSIRP FKVETSDEEIHDLHQRIDKFRFTPPLEDSCFHYGFNSNYLKKVISYWRNE FDWKKQVEILNRYPHFKTKIEGLDIHFIHVKPPQLPAGHTPKPLLMVHGW PGSFYEFYKIIPLLTDPKNHGLSDEHVFEVICPSIPGYGFSEASSKKGFN SVATARIFYKLMLRLGFQEFYIQGGDWGSLICTNMAQLVPSHVKGLHLNM ALVLSNFSTLTLLLGQRFGRFLGLTERDVELLYPVKEKVFYSLMRESGYM HIQCTKPDTVGSALNDSPVGLAAYILEKFSTWTNTEFRYLEDGGLERKFS LDDLLTNVMLYWTTGTIISSQRFYKENLGQGWMTQKHERMKVYVPTGFSA FPFELLHTPEKWVRFKYPKLISYSYMVRGGHFAAFEEPELLAQDIRKFLS VLERQ
    • 分子量
      76 kDa including tags
    • 氨基酸
      1 to 455
    • 标签
      GST tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab114694 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • EPHX
    • EPHX 1
    • Ephx1
    • EPOX
    • Epoxide hydratase
    • Epoxide hydrolase 1
    • Epoxide hydrolase 1 microsomal (xenobiotic)
    • Epoxide hydroxylase 1
    • Epoxide hydroxylase 1 microsomal (xenobiotic)
    • HYEP_HUMAN
    • HYL1
    • MEH
    • Microsomal epoxide hydrolase
    see all
  • 功能
    Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
  • 组织特异性
    Found in liver.
  • 疾病相关
    Note=In some populations, the high activity haplotype tyr113/his139 is overrepresented among women suffering from pregnancy-induced hypertension (pre-eclampsia) when compared with healthy controls.
    Defects in EPHX1 are a cause of familial hypercholanemia (FHCA) [MIM:607748]. FHCA is a disorder characterized by elevated serum bile acid concentrations, itching, and fat malabsorption.
  • 序列相似性
    Belongs to the peptidase S33 family.
  • 细胞定位
    Microsome membrane. Endoplasmic reticulum membrane.
  • Information by UniProt

Recombinant Human Epoxide hydrolase protein 图像

  • 12.5% SDS-PAGE showing ab114694 at approximately 76.12 kDa stained with Coomassie Blue.

Recombinant Human Epoxide hydrolase protein (ab114694)参考文献

ab114694 has not yet been referenced specifically in any publications.

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