Recombinant人Ephrin B2 protein (ab92862)

概述

描述

  • 性质Recombinant
  • 来源HEK 293 cells
  • 氨基酸序列
    • 种属Human
    • 氨基酸1 to 227

技术指标

Our Abpromise guarantee covers the use of ab92862 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    ELISA

    SDS-PAGE

  • 形式Lyophilised
  • 补充说明After reconstitution, store in working aliquots at -80ºC.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: PBS, pH 7.4

  • 复溶Please add 20ul of PBS to make 0.5mg/ml

常规信息

  • 别名
    • EFN B2
    • EFNB 2
    • Efnb2
    • EFNB2_HUMAN
    • Eph related receptor tyrosine kinase ligand 5
    • EPH-related receptor tyrosine kinase ligand 5
    • ephrin B2
    • Ephrin-B2
    • EphrinB2
    • EPLG 5
    • EPLG5
    • Htk L
    • HTK ligand
    • HTK-L
    • HTKL
    • LERK 5
    • LERK-5
    • LERK5
    • Ligand of eph related kinase 5
    • MGC126226
    • MGC126227
    • MGC126228
    • OTTMUSP00000024973
    see all
  • 功能Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.
    (Microbial infection) Acts as a receptor for Hendra virus and Nipah virus.
  • 组织特异性Lung and kidney.
  • 序列相似性Belongs to the ephrin family.
    Contains 1 ephrin RBD (ephrin receptor-binding) domain.
  • 翻译后修饰Inducible phosphorylation of tyrosine residues in the cytoplasmic domain.
  • 细胞定位Membrane.
  • Information by UniProt

Recombinant Human Ephrin B2 protein 图像

  • 10% SDS-PAGE of ab92862 stained with Coomassie Blue (CB) and immunoblotted with polyclonal antibody against Human Ephrin B2 (WB)

Recombinant Human Ephrin B2 protein (ab92862)参考文献

ab92862 has not yet been referenced specifically in any publications.

Product Wall

Purity: ³95% (SDS-PAGE)

Expressed in HEK293 cells

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Thank you for your enquiry.

Yes, it is the fusion protein (472 aa with tag, MWt 52.9kDa) that is at 1mg/ml concentration. The mass of the fusion protein includes the 6x His tag.

I hope this is helpful. Please contact me again if you...

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Vielen Dank für Ihre Geduld! Endlich (!) hat das Labor, welches ab92862 herstellt, sich mit der Information zur Konstruktion des Ephrin B2-Fc-Chimärproteins gemeldet. Es besteht vom N- zum C-Terminus aus: EphrinB2 -IgG1Fc -Histag (Details siehe An...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"