Recombinant人Ephrin B2 protein (ab113609)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP52799
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMGSHMIVLEPIYWNSSNSKFLPGQGLVLYP QIGDKLDIICPKVDSKTVGQYEYYKVYMVDKDQADRCTIKKENTPLLNCA KPDQDIKFTIKFQEFSPNLWGLEFQKNKDYYIISTSNGSLEGLDNQEGGV CQTRAMKILMKVGQDASSAGSTRNKDPTRRPELEAGTNGRSSTTSPFVKP NPGSSTDGNSAGHSGNNILGSEVALFA
    • 分子量25 kDa including tags
    • 氨基酸28 to 229
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab113609 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度> 85 % SDS-PAGE.
    ab113609 was purified to > 85% by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.03% DTT, 20% Glycerol, 1.17% Sodium chloride

常规信息

  • 别名
    • EFN B2
    • EFNB 2
    • Efnb2
    • EFNB2_HUMAN
    • Eph related receptor tyrosine kinase ligand 5
    • EPH-related receptor tyrosine kinase ligand 5
    • ephrin B2
    • Ephrin-B2
    • EphrinB2
    • EPLG 5
    • EPLG5
    • Htk L
    • HTK ligand
    • HTK-L
    • HTKL
    • LERK 5
    • LERK-5
    • LERK5
    • Ligand of eph related kinase 5
    • MGC126226
    • MGC126227
    • MGC126228
    • OTTMUSP00000024973
    see all
  • 功能Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.
    (Microbial infection) Acts as a receptor for Hendra virus and Nipah virus.
  • 组织特异性Lung and kidney.
  • 序列相似性Belongs to the ephrin family.
    Contains 1 ephrin RBD (ephrin receptor-binding) domain.
  • 翻译后修饰Inducible phosphorylation of tyrosine residues in the cytoplasmic domain.
  • 细胞定位Membrane.
  • Information by UniProt

Recombinant Human Ephrin B2 protein 图像

  • 15% SDS-PAGE analysis of ab113609 (3µg)

Recombinant Human Ephrin B2 protein (ab113609)参考文献

ab113609 has not yet been referenced specifically in any publications.

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