Recombinant人ELF5 protein (ab116821)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ9UKW6
    • 种属Human
    • 序列SRTSLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKSEALAKMW GQRKKNDRMTYEKLSRALRYYYKTGILERVDRRLVYKFGKNAHGWQED
    • 分子量36 kDa including tags
    • 氨基酸166 to 263

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技术指标

Our Abpromise guarantee covers the use of ab116821 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    ELISA

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • E74 like factor 5
    • E74 like factor 5 (ets domain transcription factor)
    • E74-like factor 5
    • ELF 5
    • ELF5
    • ELF5_HUMAN
    • Epithelium restricted ESE 1 related Ets factor
    • Epithelium restricted ESE1 related Ets factor
    • Epithelium specific Ets transcription factor 2
    • Epithelium-restricted ESE-1-related Ets factor
    • Epithelium-specific Ets transcription factor 2
    • ESE 2
    • ESE-2
    • ESE2
    • Ets domain TF
    • Ets domain transcription factor
    • ETS related transcription factor Elf 5
    • ETS related transcription factor Elf5
    • ETS-related transcription factor Elf-5
    see all
  • 功能Transcriptionally activator that may play a role in regulating the later stages of keratinocytes terminal differentiation.
    Isoform 2 binds to DNA sequences containing the consensus nucleotide core sequence GGA[AT]. Transcriptionally activates SPRR2A and the parotid gland-specific PSP promoters.
  • 组织特异性Expressed exclusively in tissues with a high content of epithelial cells. Highly expressed in salivary gland, mammary gland, kidney and prostate. Weakly expressed in placenta and lung. Isoform 1 and isoform 2 are differentially expressed in different tissues. In the kidney, only isoform 1 was expressed, while prostate expressed both isoforms, with levels of isoform 2 being higher. Expression is up-regulated during keratinocyte differentiation. Several epithelial carcinoma cell lines showed lack of expression.
  • 序列相似性Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
    Contains 1 PNT (pointed) domain.
  • 结构域The PNT domain acts as a transcriptional activator.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human ELF5 protein 图像

  • 12.5% SDS-PAGE stained with Coomassie Blue showing ab116821 at approximately 36.41 kDa.

Recombinant Human ELF5 protein (ab116821)参考文献

ab116821 has not yet been referenced specifically in any publications.

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