Recombinant人EIF3S1 protein (ab113578)

概述

  • 产品名称
    Recombinant人EIF3S1 protein
  • 蛋白长度
    Protein fragment

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHHSSGLVPRGSHMKISEKKKIAEKIKEKERQQKKRQEEIKKR LEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAM NPSSRDDFTEFGKLLKDKITQYEKSLYYASFLEVLVRDVCISLEIDDLKK ITNSLTVLCSEKQKQEKQSKAKKKKKGVVPGGGLKATMKDDLADYGGYDG GYVQDYEDFM
    • 分子量
      24 kDa including tags
    • 氨基酸
      70 to 258
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab113578 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度
    > 90 % SDS-PAGE.
    ab113578 is purified using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% Tris HCl, 0.03% DTT, 10% Glycerol, 1.17% Sodium chloride

常规信息

  • 别名
    • eIF 3 alpha
    • eIF-3-alpha
    • eIF3 alpha
    • eIF3 p35
    • eIF3j
    • EIF3J_HUMAN
    • EIF3S 1
    • EIF3S1
    • Eukaryotic translation initiation factor 3 subunit 1
    • Eukaryotic translation initiation factor 3 subunit J
    • Eukaryotic translation initiation factor 3, subunit 1 (alpha, 35kD)
    • Eukaryotic translation initiation factor 3, subunit 1 alpha, 35kD
    see all
  • 功能
    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regulate the interaction between the 43S PIC and mRNA.
  • 序列相似性
    Belongs to the eIF-3 subunit J family.
  • 翻译后修饰
    Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt

图片

  • 15% SDS-PAGE showing ab113578 at approximately 24.0kDa (3µg).

文献

ab113578 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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