Recombinant人EDG1 protein (ab114275)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP21453
    • 种属Human
    • 序列MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKL
    • 分子量31 kDa including tags
    • 氨基酸1 to 47

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技术指标

Our Abpromise guarantee covers the use of ab114275 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • CD363
    • CHEDG 1
    • CHEDG1
    • D1S3362
    • ECGF 1
    • ECGF1
    • EDG 1
    • EDG1
    • endothelial differentiation G protein coupled receptor 1
    • Endothelial differentiation G-protein coupled receptor 1
    • Endothelial differentiation sphingolipid G protein coupled receptor 1
    • FLJ58121
    • G protein coupled sphingolipid receptor
    • g protein-coupled receptor edg-1
    • S1P receptor 1
    • S1P receptor Edg 1
    • S1P receptor Edg-1
    • S1P receptor Edg1
    • S1P(1) receptor
    • S1P1
    • s1pr1
    • S1PR1_HUMAN
    • sphingolipid g-protein-coupled receptor 1
    • Sphingosine 1 phosphate receptor Edg 1
    • Sphingosine 1 phosphate receptor EDG1
    • sphingosine 1- phosphate receptor 1
    • Sphingosine 1-phosphate receptor 1
    • Sphingosine 1-phosphate receptor Edg-1
    • Sphingosine 1phosphate receptor type 1 S1P1
    see all
  • 功能Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells. Seems to be coupled to the G(i) subclass of heteromeric G proteins.
  • 组织特异性Endothelial cells, and to a lesser extent, in vascular smooth muscle cells, fibroblasts, melanocytes, and cells of epithelioid origin.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 翻译后修饰S1P-induced endothelial cell migration requires the PKB/AKT1-mediated phosphorylation of the third intracellular loop at the Thr-236 residue.
  • 细胞定位Cell membrane.
  • Information by UniProt

Recombinant Human EDG1 protein 图像

  • 12.5% SDS-PAGE analysis of ab114275 stained with Coomassie Blue.

Recombinant Human EDG1 protein (ab114275)参考文献

ab114275 has not yet been referenced specifically in any publications.

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