Recombinant人EBI3 protein (ab83026)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ14213
    • 种属Human
    • 序列RKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPV SFIATYRL GMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSF VP FITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYW IRYKRQGAARFHRV GPIEATSFILRAVRPRARYYVQVAAQDLTDYGEL SDWSLPATATMSLGK
    • 氨基酸21 to 229
    • 标签His tag N-Terminus
    • 额外的序列信息This aa sequence represents the mature full length minus the signal peptide from aa 1 to 20. The His tag is a hexahistidine tag.

技术指标

Our Abpromise guarantee covers the use of ab83026 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

  • 纯度> 95 % SDS-PAGE.

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

    Preservative: None
    Constituents: 50% Glycerol, PBS, pH 7.2

常规信息

  • 别名
    • cytokine receptor
    • EBI3
    • EBV induced gene 3 protein
    • EBV-induced gene 3 protein
    • Epstein Barr virus induced 3
    • Epstein Barr virus induced gene 3
    • Epstein Barr virus induced gene 3 protein
    • Epstein-Barr virus-induced gene 3 protein
    • IL 27 subunit beta
    • IL 27B
    • IL-27 subunit beta
    • IL-27B
    • IL27 subunit
    • IL27 subunit beta
    • IL27B
    • IL27B_HUMAN
    • IL35 subunit
    • interleukin 27 subunit beta
    • Interleukin-27 subunit beta
    see all
  • 功能Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.
  • 序列相似性Belongs to the type I cytokine receptor family. Type 3 subfamily.
    Contains 2 fibronectin type-III domains.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant Human EBI3 protein 图像

  • SDS-PAGE showing ab83026.

  • Anti-EBI3 antibody (ab72330) at 2 µg/ml (Sample: ab83026, 0.1 ug)

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

Recombinant Human EBI3 protein (ab83026)参考文献

ab83026 has not yet been referenced specifically in any publications.

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