Recombinant人EB2 protein (ab113592)

概述

  • 产品名称Recombinant人EB2 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ15555
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMPGPTQTLSPNGENNNDIIQDNNGTIIPFR KHTVRGERSYSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQ LCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNV DKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIP PPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSS GSASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQ EHGQENDDLVQRLMDILYASEEHEGHTEEPEAEEQAHEQQPPQQEEY
    • 分子量39 kDa including tags
    • 氨基酸1 to 327
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab113592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度> 85 % SDS-PAGE.
    ab113592 was purified using conventional chromatography.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride, 0.02% DTT

常规信息

  • 别名
    • APC binding protein EB1
    • APC binding protein EB2
    • APC-binding protein EB2
    • EB1
    • EB2
    • End binding protein 2
    • End-binding protein 2
    • H.sapiens mRNA for novel T cell activation protein
    • MAPRE2
    • MARE2_HUMAN
    • Microtubule associated protein RP/EB family member 2
    • Microtubule-associated protein RP/EB family member 2
    • RP1
    • T cell activation protein EB1 family
    see all
  • 功能May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.
  • 组织特异性Expressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes.
  • 序列相似性Belongs to the MAPRE family.
    Contains 1 CH (calponin-homology) domain.
    Contains 1 EB1 C-terminal domain.
  • 结构域Composed of two functionally independent domains. The N-terminal domain forms an hydrophobic cleft involved in microtubule binding and the C-terminal is involved in the formation of mutually exclusive complexes with APC and DCTN1.
  • 细胞定位Cytoplasm > cytoskeleton. Associated with the microtubule network. Accumulates at the plus end of microtubules.
  • Information by UniProt

Recombinant Human EB2 protein 图像

  • 15% SDS-PAGE analysis of ab113592 (3µg)

Recombinant Human EB2 protein (ab113592)参考文献

ab113592 has not yet been referenced specifically in any publications.

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