重组人E2F8蛋白(ab153513)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: WB, ELISA
描述
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产品名称
重组人E2F8蛋白 -
表达系统
Wheat germ -
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMELT APSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTP PQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAP ERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPS GYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELT AVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNF TLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYD SPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSS SCMDFEGANKTSLGTLFVPQRKLEVSTEDVH -
氨基酸
1 to 431 -
标签
GST tag N-Terminus
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技术指标
Our Abpromise guarantee covers the use of ab153513 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Western blot
ELISA
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形式
Liquid -
补充说明
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
常规信息
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别名
- E2F 8
- E2F family member 82
- E2F transcription factor 8
see all -
功能
Along with E2F7, inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Directly represses E2F1 transcription. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession. -
序列相似性
Belongs to the E2F/DP family. -
结构域
Both DNA-binding domains are required for DNA-binding and are proposed to form an intramolecular structure that is similar to the winged helix structure of the E2F-DP heterodimer. -
细胞定位
Nucleus. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab153513 尚未被引用在任何文献中。