Recombinant人E2F6 protein (ab114573)

概述

  • 产品名称Recombinant人E2F6 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionO75461
    • 种属Human
    • 序列MSQQRPARKLPSLLLDPTEETVRRRCRDPINVEGLLPSKIRINLEDNVQY VSMRKALKVKRPRFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRK RRVYDITNVLDGIDLVEKKSKNHIRWIGSDLSNFGAVPQQKKLQEELSDL SAMEDALDELIKDCAQQLFELTDDKENERLAYVTYQDIHSIQAFHEQIVI AVKAPAETRLDVPAPREDSITVHIRSTNGPIDVYLCEVEQGQTSNKRSEG VGTSSSESTHPEGPEEEENPQQSEELLEVSN
    • 分子量57 kDa
    • 氨基酸1 to 281

技术指标

Our Abpromise guarantee covers the use of ab114573 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

    ELISA

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • E2F 6
    • E2F binding site modulating activity protein
    • E2F transcription factor 6
    • E2F transcription factor 6 isoform 1
    • E2F-6
    • E2F6
    • E2F6_HUMAN
    • EMA
    • MGC111545
    • Transcription factor E2F6
    see all
  • 功能Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F-6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase.
  • 组织特异性Expressed in all tissues examined. Highest levels in placenta, skeletal muscle, heart, ovary, kidney, small intestine and spleen.
  • 序列相似性Belongs to the E2F/DP family.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human E2F6 protein 图像

  • 12.5% SDS-PAGE Stained with Coomassie Blue

Recombinant Human E2F6 protein (ab114573)参考文献

ab114573 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab114573.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"