概述

  • 产品名称
    Recombinant人DTYMK protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHH SSGLVPRGSH MAARRGALIV LEGVDRAGKS TQSRKLVEAL CAAGHRAELL RFPERSTEIG KLLSSYLQKK SDVEDHSVHL LFSANRWEQV PLIKEKLSQG VTLVVDRYAF SGVAFTGAKE NFSLDWCKQP DVGLPKPDLV LFLQLQLADA AKRGAFGHER YENGAFQERA LRCFHQLMKD TTLNWKMVDA SKSIEAVHED IRVLSEDAIR TATEKPLGEL WK
    • 分子量
      24 kDa
    • 氨基酸
      1 to 212
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab109838 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度
    > 95 % SDS-PAGE.
    No detergents such as urea, Triton or Tween have been used to purify the protein. Purified by using anion exchange chromatography (DEAE sepharose resin) and gel filtration chromatography (Sephacryl S 200) with 20mM Tris pH 7.5, 2mM EDTA.
  • 形式
    Liquid
  • 补充说明


    Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.04% DTT, 0.58% Sodium chloride

常规信息

  • 别名
    • CDC8
    • deoxythymidylate kinase
    • Deoxythymidylate kinase (thymidylate kinase)
    • dTMP kinase
    • Dtymk
    • FLJ44192
    • KTHY_HUMAN
    • MGC198617
    • OTTHUMP00000164604
    • OTTHUMP00000200145
    • OTTHUMP00000200146
    • PP3731
    • Thymidylate kinase
    • TMPK
    • TYMK
    see all
  • 功能
    Catalyzes the conversion of dTMP to dTDP.
  • 通路
    Pyrimidine metabolism; dTTP biosynthesis.
  • 序列相似性
    Belongs to the thymidylate kinase family.
  • Information by UniProt

图片

  • SDS-PAGE analysis of ab109838: (1) MW marker, (2) ab109838 at 3µg
    Gel concentration: 15%

文献

This product has been referenced in:
  • Su JY & Sclafani RA Molecular cloning and expression of the human deoxythymidylate kinase gene in yeast. Nucleic Acids Res 19:823-7 (1991). Read more (PubMed: 2017365) »
  • Cummins RR & Balinsky D Activities of some enzymes of pyrimidine and DNA synthesis in a rat transplantable hepatoma and human primary hepatomas, in cell lines derived from these tissues, and in human fetal liver. Cancer Res 40:1235-9 (1980). Read more (PubMed: 6244089) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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