Recombinant人Dopamine D2 Receptor protein (ab112281)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP14416
    • 种属Human
    • 序列MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVF GNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVG EW KFSRIHCDIF
    • 分子量38 kDa including tags
    • 氨基酸1 to 110
    • 标签GST tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab112281 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性useful for Antibody Production and Protein Array
  • 应用

    Western blot

    SDS-PAGE

    ELISA

    Peptide Array

  • 形式Liquid
  • 补充说明Best use within three months from the date of receipt of this protein.useful for Antibody Production and Protein Array
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione
    Note: Reduced glutathione

常规信息

  • 别名
    • D(2) dopamine receptor
    • D2 dopamine receptor
    • D2DR
    • D2R
    • Dopamine D2 receptor
    • Dopamine receptor D2
    • DRD 2
    • DRD2
    • DRD2_HUMAN
    see all
  • 功能This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
  • 疾病相关Defects in DRD2 are associated with dystonia type 11 (DYT11) [MIM:159900]; also known as alcohol-responsive dystonia. DYT11 is a myoclonic dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. DYT11 is characterized by involuntary lightning jerks and dystonic movements and postures alleviated by alcohol. Inheritance is autosomal dominant. The age of onset, pattern of body involvement, presence of myoclonus and response to alcohol are all variable.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位Cell membrane.
  • Information by UniProt

Recombinant Human Dopamine D2 Receptor protein 图像

  • 12.5% SDS-PAGE Stained with Coomassie Blue with recombinant protein.

Recombinant Human Dopamine D2 Receptor protein (ab112281)参考文献

ab112281 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"