Recombinant人DOPA Decarboxylase protein (ab40029)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab40029 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5

常规信息

  • 别名
    • AADC
    • Aromatic L Amino Acid Decarboxylase
    • Aromatic-L-amino-acid decarboxylase
    • DDC
    • DDC_HUMAN
    • DOPA decarboxylase
    • DOPA decarboxylase (aromatic L-amino acid decarboxylase)
    see all
  • 功能Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
  • 通路Catecholamine biosynthesis; dopamine biosynthesis; dopamine from L-tyrosine: step 2/2.
  • 疾病相关Defects in DDC are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD) [MIM:608643]. AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. It causes developmental and psychomotor delay, poor feeding, lethargy, ptosis, intermittent hypothermia, gastrointestinal disturbances. The onset is early in infancy and inheritance is autosomal recessive.
  • 序列相似性Belongs to the group II decarboxylase family.
  • Information by UniProt

Recombinant Human DOPA Decarboxylase protein 图像

Recombinant Human DOPA Decarboxylase protein (ab40029)参考文献

ab40029 has not yet been referenced specifically in any publications.

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