Recombinant人DOCK7 protein (ab92221)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列DLDEQEFVYKEPAITKLAEISHRLEGFYGERFGEDVVEVIKDSNPVDKCK LDP NKAYIQITYVEPYFDTYEMKDRITYFDKNYNLRRFMYCTPFTLDG RAHGELHE QFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVAIED MQKKTQELAFATH QDPADPKMLQMVLQGSVGTTVNQGPLEVAQVFLSE IPSDPKLFRHHNKLRLCF KDFTKRCEDALRKNKSLIGPDQKEYQRELE RNYHRLKEALQPLINRKIPQLYK AVLPVTCHRDSFSRMSLRKMDL
    • 氨基酸1823 to 2109

技术指标

Our Abpromise guarantee covers the use of ab92221 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 形式Lyophilised
  • 补充说明Protein Identity confirmed by Mass Spectrometry (MS/MS) (acquired on initial reference batch)
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5

  • 复溶reconstitution with 69 µl aqua dest.

常规信息

  • 别名
    • 3110056M06Rik
    • dedicator of cytokinesis 7
    • Dedicator of cytokinesis protein 7
    • Gm430
    • KIAA1771
    • MGC189434
    • mKIAA1771
    • RP23 329P19.2
    • ZIR2
    see all
  • 相关性DOCK7 functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. It does not have a GEF activity for CDC42. It is required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization.
  • 细胞定位Cell projection, axon. Note=Enriched in the developing axons of hippocampal neurons.

Recombinant Human DOCK7 protein 图像

  • The image shows an electrophoretic assay performed using an Agilent 5100 ALP. In some images colored control bands can be seen at 15 kDa (green) and/or 240 kDa (purple). The protein-specific band is blue.

Recombinant Human DOCK7 protein (ab92221)参考文献

ab92221 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"