Recombinant人Dnmt3L protein (ab112413)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ9UJW3
    • 种属Human
    • 序列LVLNKEDLDVASRFLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSSRHWA LVSEEELSLLAQNKQSSKLAAKWPTKLVKNCFLPLREYFKYFSTELTSSL
    • 分子量37 kDa including tags
    • 氨基酸288 to 387

技术指标

Our Abpromise guarantee covers the use of ab112413 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性This product is useful for Antibody Production and Protein Array
  • 应用

    ELISA

    Western blot

    Peptide Array

    SDS-PAGE

  • 形式Liquid
  • 补充说明Best used within three months from the date of receipt This product is useful for Antibody Production and Protein Array
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione
    Note: Glutathione is reduced.

常规信息

  • 别名
    • Cytosine 5 methyltransferase 3 like protein
    • DNA (cytosine 5 ) methyltransferase 3 like
    • DNA (cytosine-5)-methyltransferase 3-like
    • DNA cytosine 5 methyltransferase 3 like protein
    • DNA methyltransferase 3 like protein
    • DNM3L_HUMAN
    • Dnmt 3L
    • Dnmt3l
    • Human cytosine 5 methyltransferase 3 like protein
    • MGC1090
    see all
  • 功能Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.
  • 组织特异性Expressed at low levels in several tissues including testis, ovary, and thymus.
  • 序列相似性Belongs to the C5-methyltransferase family.
    Contains 1 ADD-type zinc finger.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human Dnmt3L protein 图像

  • 12.5% SDS-PAGE image, using ab112413. (Stained with Coomassie Blue)

Recombinant Human Dnmt3L protein (ab112413)参考文献

ab112413 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"