Recombinant人DNAJC3 protein (ab114761)

概述

  • 产品名称
    Recombinant人DNAJC3 protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAA GQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQL KMDFTAARLQRGHLLLKQGKLDEAEDDFKKVVFPVPSLLGLQRSLLDDLY LLFWFFLMKKVTFRCLSSAISECLPQSLNLMKFNLLISFLLLWTVRLVSC LRSIHYAVGSKTFLISSKSFMVLCFIFKPIVYLS
    • 分子量
      52 kDa including tags
    • 氨基酸
      1 to 234

相关产品

技术指标

Our Abpromise guarantee covers the use of ab114761 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 µg/ul.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • DnaJ (Hsp40) homolog subfamily C member 3
    • DnaJ homolog subfamily C member 3
    • DNAJC3
    • DNJC3_HUMAN
    • double-stranded RNA-activated protein kinase inhibitor
    • Endoplasmic reticulum DnaJ protein 6
    • ERdj6
    • HP58
    • Interferon induced, double stranded RNA activated protein kinase inhibitor
    • Interferon-induced
    • P58
    • p58 ipk
    • P58IPK
    • PRKRI
    • Protein kinase inhibitor of 58 kDa
    • Protein kinase inhibitor p58
    • Protein kinase interferon inducible double stranded RNA dependent inhibitor
    see all
  • 功能
    Involved in the unfolded protein response (UPR) during ER stress. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
  • 组织特异性
    Widely expressed with high level in the pancreas and testis. Also expressed in cell lines with different levels.
  • 序列相似性
    Contains 1 J domain.
    Contains 9 TPR repeats.
  • 结构域
    The J domain mediates interaction with HSPA8.
  • 细胞定位
    Endoplasmic reticulum.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE Stained with Coomassie Blue showing ab114761 at approximately 51.85kDa.

文献

ab114761 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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