Recombinant人DNAJC3 protein (ab114761)

概述

  • 产品名称Recombinant人DNAJC3 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ13217
    • 种属Human
    • 序列MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAA GQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQL KMDFTAARLQRGHLLLKQGKLDEAEDDFKKVVFPVPSLLGLQRSLLDDLY LLFWFFLMKKVTFRCLSSAISECLPQSLNLMKFNLLISFLLLWTVRLVSC LRSIHYAVGSKTFLISSKSFMVLCFIFKPIVYLS
    • 分子量52 kDa including tags
    • 氨基酸1 to 234

技术指标

Our Abpromise guarantee covers the use of ab114761 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 µg/ul.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • DnaJ (Hsp40) homolog subfamily C member 3
    • DnaJ homolog subfamily C member 3
    • DNAJC3
    • DNJC3_HUMAN
    • double-stranded RNA-activated protein kinase inhibitor
    • Endoplasmic reticulum DnaJ protein 6
    • ERdj6
    • HP58
    • Interferon induced, double stranded RNA activated protein kinase inhibitor
    • Interferon-induced
    • P58
    • p58 ipk
    • P58IPK
    • PRKRI
    • Protein kinase inhibitor of 58 kDa
    • Protein kinase inhibitor p58
    • Protein kinase interferon inducible double stranded RNA dependent inhibitor
    see all
  • 功能Involved in the unfolded protein response (UPR) during ER stress. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
  • 组织特异性Widely expressed with high level in the pancreas and testis. Also expressed in cell lines with different levels.
  • 序列相似性Contains 1 J domain.
    Contains 9 TPR repeats.
  • 结构域The J domain mediates interaction with HSPA8.
  • 细胞定位Endoplasmic reticulum.
  • Information by UniProt

Recombinant Human DNAJC3 protein 图像

  • 12.5% SDS-PAGE Stained with Coomassie Blue showing ab114761 at approximately 51.85kDa.

Recombinant Human DNAJC3 protein (ab114761)参考文献

ab114761 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"