Recombinant人DNA Polymerase beta protein (ab111641)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP06746
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMSKRKAPQETLNGGITDMLTELANFEKNVS QAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATG KLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNED KLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSK GETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNK NMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREP KDRSE
    • 分子量40 kDa including tags
    • 氨基酸1 to 335
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab111641 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab111641 is purified using conventional chromatography.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 30% Glycerol, 0.02% DTT, 0.58% Sodium chloride, 69% Tris HCl

常规信息

  • 别名
    • DNA directed DNA polymerase beta
    • DNA pol beta
    • DNA polymerase beta
    • DNA polymerase beta subunit
    • DPOLB_HUMAN
    • MGC125976
    • Pol B
    • Pol beta
    • POLB
    • Polymerase (DNA directed) beta
    see all
  • 功能Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
  • 序列相似性Belongs to the DNA polymerase type-X family.
  • 结构域Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.
  • 翻译后修饰Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human DNA Polymerase beta protein 图像

  • 15% SDS-PAGE analysis of ab111641 (3 µg)

Recombinant Human DNA Polymerase beta protein (ab111641)参考文献

ab111641 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"