概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MLRSLLLHSLRLCAQTASCLVLFPRFLGTAFMLWLLDFLCIRKHFLGRRR RGQPEPEVELNSEGEEVPPDDPPICVSDDNRLCTLASLKAVWHGQKLDFF KQAHEGGPAPNSEVVLPDGFQSQHILDYAQGNRPLVLNFGSCT
    • 分子量
      41 kDa including tags
    • 氨基酸
      1 to 143

技术指标

Our Abpromise guarantee covers the use of ab152332 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    Western blot

    SDS-PAGE

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • 5DIII
    • D3
    • Deiodinase iodothyronine type 3
    • Deiodinase iodothyronine type III
    • Dio 3
    • Dio3
    • DIOIII
    • IOD3_HUMAN
    • Iodothyronine deiodinase placental type
    • MGC124117
    • MGC124118
    • Thyroxine deiodinase type III
    • Thyroxine deiodinase type III (selenoprotein)
    • TXDI3
    • Type 3 DI
    • Type 3 iodothyronine selenodeiodinase
    • Type III 5' deiodinase
    • Type III iodothyronine deiodinase
    • Type-III 5''-deiodinase
    see all
  • 功能
    Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.
  • 组织特异性
    Expressed in placenta and several fetal tissues.
  • 序列相似性
    Belongs to the iodothyronine deiodinase family.
  • 细胞定位
    Cell membrane. Endosome membrane.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE analysis of ab152332 stained with Coomassie Blue.

文献

ab152332 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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