概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      PSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRM DNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFSKR
    • 分子量
      37 kDa including tags
    • 氨基酸
      166 to 265

相关产品

技术指标

Our Abpromise guarantee covers the use of ab152331 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • 5DII
    • D2
    • Deiodinase, iodothyronine, type II
    • DIO2
    • DIOII
    • EC 1.97.1.10
    • IOD2_HUMAN
    • ITDI2
    • SelY
    • Thyroxine deiodinase, type II
    • TXDI2
    • Type 2 DI
    • Type 2 iodothyronine deiodinase
    • Type II 5' deiodinase
    • Type II iodothyronine deiodinase
    • Type-II 5''-deiodinase
    see all
  • 功能
    Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development.
  • 组织特异性
    Heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain.
  • 序列相似性
    Belongs to the iodothyronine deiodinase family.
  • 翻译后修饰
    Ubiquitinated by MARCH6, leading to its degradation by the proteasome. Deubiquitinated by USP20 and USP33.
  • 细胞定位
    Membrane.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE analysis of ab152331 stained with Coomassie Blue.

文献

ab152331 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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