Recombinant人DFNA5/GSDME protein (ab116824)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFWCWQRPK YQFLSLTLGDVLIEDQFPSPVVVESDFVKYEGKFANHVSGTLETALGKVK LNLGGSSRVESQSSFGTLRKQEVDLQQLIRDSAERTINLRNPVLQQVLEG RNEVLCVLTQKITTMQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGN VTKDSNVVLEIPAATTIAYGVIELYVKLDGQFEFCLLRGKQGGFENKKRI DSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSVLKQATLLLERNFHPFA ELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAVLGELKP RQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSA AALLGTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQR LFASADISLERLKSSVKAVILKDSKVFPLLLCITLNGLCALGREHS
    • 分子量
      81 kDa including tags
    • 氨基酸
      1 to 496

技术指标

Our Abpromise guarantee covers the use of ab116824 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • 2310037D07Rik
    • 4932441K13Rik
    • Deafness, autosomal dominant 5
    • Deafness, autosomal dominant 5 protein
    • DFNA5
    • DFNA5 gene
    • DFNA5_HUMAN
    • Dfna5h
    • EG14210
    • Fin15
    • ICERE 1
    • ICERE-1
    • Inversely correlated with estrogen receptor expression 1
    • Non-syndromic hearing impairment protein 5
    • Nonsyndromic hearing impairment protein
    see all
  • 组织特异性
    Expressed in cochlea. Low level of expression in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas, with highest expression in placenta.
  • 疾病相关
    Defects in DFNA5 are the cause of deafness autosomal dominant type 5 (DFNA5) [MIM:600994]. DFNA5 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
  • 序列相似性
    Belongs to the gasdermin family.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE stained with Coomassie Blue showing ab116824 at approximately 80.63 kDa.

文献

ab116824 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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