Recombinant人delta Sarcoglycan protein (ab116758)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ92629
    • 种属Human
    • 序列ILNDQTKVLTQLITGPKAVEAYGKKFEVKTVSGKLLFSADNNEVVVGAER LRVLGAEGTVFPKSIETPNVRADPFK
    • 分子量34 kDa
    • 氨基酸113 to 188

技术指标

Our Abpromise guarantee covers the use of ab116758 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

常规信息

  • 别名
    • 35 kDa dystrophin associated glycoprotein
    • 35 kDa dystrophin-associated glycoprotein
    • 35DAG
    • CMD1L
    • DAGD
    • Delta-sarcoglycan
    • Delta-SG
    • Dystrophin associated glycoprotein delta sarcoglycan
    • LGMD2F
    • MGC22567
    • Placental delta sarcoglycan
    • Sarcoglycan delta (35 kDa dystrophin associated glycoprotein)
    • SG delta
    • SGCD
    • SGCD_HUMAN
    • SGCDP
    • SGD
    see all
  • 功能Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
  • 组织特异性Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung.
  • 疾病相关Defects in SGCD are the cause of limb-girdle muscular dystrophy type 2F (LGMD2F) [MIM:601287]. LGMD2F is an autosomal recessive disorder.
    Defects in SGCD are the cause of cardiomyopathy dilated type 1L (CMD1L) [MIM:606685]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
  • 序列相似性Belongs to the sarcoglycan beta/delta/gamma/zeta family.
  • 翻译后修饰Glycosylated.
    Disulfide bonds are present.
  • 细胞定位Cell membrane > sarcolemma. Cytoplasm > cytoskeleton.
  • Information by UniProt

Recombinant Human delta Sarcoglycan protein 图像

  • 12.5% SDS-PAGE analysis of ab116758 at approximately 33.99kDa, stained with Coomassie Blue.

Recombinant Human delta Sarcoglycan protein (ab116758)参考文献

ab116758 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab116758.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"