Recombinant人delta 1 Catenin protein (ab114472)

概述

  • 产品名称Recombinant人delta 1 Catenin protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ96FS1
    • 种属Human
    • 序列WGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDDSTLPLIDRNQKS DKKPDREEIQMSNMGSNTKSLDNNYSTPNERGDHNKTLDRSGDLGDMEPL KGTTPLMQKI
    • 分子量38 kDa including tags
    • 氨基酸721 to 830

技术指标

Our Abpromise guarantee covers the use of ab114472 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    ab114472 is best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

常规信息

  • 别名
    • Cadherin associated Src substrate
    • Cadherin-associated Src substrate
    • CAS
    • Catenin (cadherin associated protein) delta 1
    • Catenin delta
    • Catenin delta 1
    • Catenin delta-1
    • CTND1_HUMAN
    • CTNND
    • CTNND 1
    • CTNND1
    • KIAA0384
    • p120
    • P120 CAS
    • p120 catenin
    • P120 CTN
    • p120(cas)
    • p120(ctn)
    • P120CAS
    • P120CTN
    see all
  • 功能Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
  • 组织特异性Expressed in vascular endothelium.
  • 序列相似性Belongs to the beta-catenin family.
    Contains 10 ARM repeats.
  • 结构域A possible nuclear localization signal exists in all isoforms where Asp-626--631-Arg are deleted.
  • 翻译后修饰Phosphorylated by protein-tyrosine kinases. Dephosphorylated by PTPRJ.
  • 细胞定位Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
  • Information by UniProt

Recombinant Human delta 1 Catenin protein 图像

  • ab114472 analysed on a 12.5% SDS-PAGE stained with Coomassie Blue.

Recombinant Human delta 1 Catenin protein (ab114472)参考文献

ab114472 has not yet been referenced specifically in any publications.

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