The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml. ab114472 is best used within three months from the date of receipt.
Concentration information loading...
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.79% Tris HCl, 0.3% Glutathione
Cadherin associated Src substrate
Cadherin-associated Src substrate
Catenin (cadherin associated protein) delta 1
Catenin delta 1
Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
Expressed in vascular endothelium.
Belongs to the beta-catenin family. Contains 10 ARM repeats.
A possible nuclear localization signal exists in all isoforms where Asp-626--631-Arg are deleted.
Phosphorylated by protein-tyrosine kinases. Dephosphorylated by PTPRJ.
Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.