The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
补充说明Protein concentration is above or equal to 0.05 mg/ml. ab114616 is best used within three months from the date of receipt.
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
ATP dependent RNA helicase DDX3X
ATP-dependent RNA helicase DDX3X
DEAD (Asp Glu Ala Asp) box polypeptide 3 X linked
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DEAD box protein 3
DEAD box protein 3 X-chromosomal
DEAD box X isoform
DEAD box, X isoform
DEAD/H (Asp Glu Ala Asp/His) box polypeptide 3
DEAD/H box 3
DEAD/H box 3, X-linked
Helicase like protein 2
Helicase-like protein 2
功能ATP-dependent RNA helicase. Acts as a cofactor for XPO1-mediated nuclear export of incompletely spliced HIV-1 Rev RNAs. Also involved in HIV-1 replication. Interacts specifically with hepatitis C virus core protein resulting in a change in intracellular location.
序列相似性Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain.
细胞定位Nucleus speckle. Cytoplasm. Located predominantly in nuclear speckles and, at low levels, throughout the cytoplasm. Located to the outer side of nuclear pore complexes (NPC). Shuttles between the nucleus and the cytoplasm in a XPO1-dependent manner.