Recombinant人DDR2 protein (ab96401)



  • 性质Recombinant
  • 来源Baculovirus
  • 氨基酸序列
    • AccessionQ16832
    • 种属Human
    • 分子量70 kDa including tags
    • 氨基酸467 to 855


Our Abpromise guarantee covers the use of ab96401 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性The specific activity was determined to be 48 nmol/min/mg.
  • 应用


    Functional Studies

  • 纯度 90 % .
    Purity was determined to be >90% by densitometry.
  • 形式Liquid
  • Concentration information loading...


  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.


  • 别名
    • CD167 antigen-like family member B
    • CD167b
    • CD167b antigen
    • Cell migration inducing protein 20
    • DDR 2
    • DDR2
    • DDR2_HUMAN
    • Discoidin domain containing receptor 2
    • Discoidin domain receptor 2
    • Discoidin domain receptor family member 2
    • discoidin domain receptor tyrosine kinase 2
    • Discoidin domain-containing receptor 2
    • discoidin domain-containing receptor tyrosine kinase 2
    • Hydroxyaryl protein kinase
    • MIG20a
    • Migration inducing gene 16 protein
    • Neurotrophic tyrosine kinase
    • Neurotrophic tyrosine kinase receptor related 3
    • NTRKR 3
    • NTRKR3
    • Receptor protein tyrosine kinase TKT
    • Receptor protein-tyrosine kinase TKT
    • Receptor related 3
    • receptor-related 3
    • TKT
    • TYRO 10
    • TYRO10
    • Tyrosine kinase receptor related to neurotrophic TRK
    • Tyrosine protein kinase TYRO 10
    • Tyrosine protein kinase TYRO10
    • Tyrosine-protein kinase TYRO10
    • Tyrosylprotein kinase
    see all
  • 功能This tyrosine kinase receptor for fibrillar collagen mediates fibroblast migration and proliferation. Contributes to cutaneous wound healing.
  • 组织特异性The major 10 kDa transcript is expressed in high levels in heart and lung, less in brain, placenta, liver, skeletal muscle, pancreas, and kidney.
  • 疾病相关Defects in DDR2 are the cause of spondyloepimetaphyseal dysplasia short limb-hand type (SEMD-SL) [MIM:271665]. A bone disease characterized by short-limbed dwarfism, a narrow chest with pectus excavatum, brachydactyly in the hands and feet, a characteristic craniofacial appearance and premature calcifications. The radiological findings are distinctive and comprise short long bones throughout the skeleton with striking epiphyses that are stippled, flattened and fragmented and flared, irregular metaphyses. Platyspondyly in the spine with wide intervertebral spaces is observed and some vertebral bodies are pear-shaped with central humps, anterior protrusions and posterior scalloping.
  • 序列相似性Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
    Contains 1 F5/8 type C domain.
    Contains 1 protein kinase domain.
  • 细胞定位Membrane.
  • Information by UniProt

Recombinant human DDR2 protein 图像

  • Kinase Assay demonstrating specific activity of ab96401.
  • SDS-PAGE showing ab96401 at approximately 70kDa.

Recombinant human DDR2 protein (ab96401)参考文献

ab96401 has not yet been referenced specifically in any publications.

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