Recombinant人DCXR protein (ab98147)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ7Z4W1
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMELFLAGRRVLVTGAGKGIGRGTVQALHAT GARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLL VNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGA IVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT VVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMT TGSTLPVEGGFWAC
    • 分子量28 kDa including tags
    • 氨基酸1 to 244
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab98147 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度> 95 % SDS-PAGE.
    ab98147 was purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 50mM Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0

常规信息

  • 别名
    • Carbonyl reductase 2
    • Carbonyl reductase II
    • DCR
    • Dcxr
    • DCXR_HUMAN
    • Dicarbonyl L xylulose reductase
    • Dicarbonyl/ L xylulose reductase
    • Dicarbonyl/L-xylulose reductase
    • HCR2
    • HCRII
    • Human carbonyl reductase 2
    • kiDCR
    • Kidney dicarbonyl reductase
    • L xylulose reductase
    • L-xylulose reductase
    • P34H
    • PNTSU
    • SDR20C1
    • Short chain dehydrogenase/reductase family 20C member 1
    • Sperm surface protein P34H
    • XR
    see all
  • 功能Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
  • 组织特异性Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.
  • 疾病相关Note=The enzyme defect in pentosuria has been shown to involve L-xylulose reductase. Essential pentosuria is an inborn error of metabolism characterized by the excessive urinary excretion of the pentose L-xylulose.
  • 序列相似性Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • 细胞定位Membrane. Probably recruited to membranes via an interaction with phosphatidylinositol.
  • Information by UniProt

Recombinant Human DCXR protein 图像

  • 15% SDS-PAGE analysis of 3µg ab98147

Recombinant Human DCXR protein (ab98147)参考文献

ab98147 has not yet been referenced specifically in any publications.

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