Recombinant人DCXR protein (ab117694)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ7Z4W1
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MELFLAGRRV LVTGAGKGIG RGTVQALHAT GARVVAVSRT QADLDSLVRE CPGIEPVCVD LGDWEATERA LGSVGPVDLL VNNAAVALLQ PFLEVTKEAF DRSFEVNLRA VIQVSQIVAR GLIARGVPGA IVNVSSQCSQ RAVTNHSVYC STKGALDMLT KVMALELGPH KIRVNAVNPT VVMTSMGQAT WSDPHKAKTM LNRIPLGKFA EVEHVVNAIL FLLSDRSGMT TGSTLPVEGG FWAC
    • 分子量28 kDa including tags
    • 氨基酸1 to 244
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab117694 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab117694 is purified by proprietary chromatographic techniques
  • 形式Liquid
  • 补充说明Please prevent freeze thaw cycles.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Store under Desiccating conditions.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.02% DTT, 0.29% Sodium chloride, 20% Glycerol

常规信息

  • 别名
    • Carbonyl reductase 2
    • Carbonyl reductase II
    • DCR
    • Dcxr
    • DCXR_HUMAN
    • Dicarbonyl L xylulose reductase
    • Dicarbonyl/ L xylulose reductase
    • Dicarbonyl/L-xylulose reductase
    • HCR2
    • HCRII
    • Human carbonyl reductase 2
    • kiDCR
    • Kidney dicarbonyl reductase
    • L xylulose reductase
    • L-xylulose reductase
    • P34H
    • PNTSU
    • SDR20C1
    • Short chain dehydrogenase/reductase family 20C member 1
    • Sperm surface protein P34H
    • XR
    see all
  • 功能Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
  • 组织特异性Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.
  • 疾病相关Note=The enzyme defect in pentosuria has been shown to involve L-xylulose reductase. Essential pentosuria is an inborn error of metabolism characterized by the excessive urinary excretion of the pentose L-xylulose.
  • 序列相似性Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • 细胞定位Membrane. Probably recruited to membranes via an interaction with phosphatidylinositol.
  • Information by UniProt

Recombinant Human DCXR protein (ab117694)参考文献

ab117694 has not yet been referenced specifically in any publications.

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