Recombinant人DCK protein (ab99520)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSMATPPKRSCPSFSA SSEGTRIKKISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCNVQST QDEFEELTMSQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNG KLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNN QFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHES WLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL
    • 分子量
      35 kDa including tags
    • 氨基酸
      1 to 260
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab99520 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度
    > 90 % SDS-PAGE.
    ab99520 was purified using conventional chromatography.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 2mM EDTA, 1mM DTT, 0.1mM PMSF, pH 7.5

常规信息

  • 别名
    • dCK
    • DCK protein
    • DCK_HUMAN
    • Deoxycytidine kinase
    • Deoxynucleoside kinase
    • EC 2.7.1
    • EC 2.7.1.74
    • MGC117410
    • MGC138632
    • OTTHUMP00000219118
    • OTTHUMP00000219119
    see all
  • 功能
    Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.
  • 序列相似性
    Belongs to the DCK/DGK family.
  • 翻译后修饰
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位
    Nucleus.
  • Information by UniProt

图片

  • 15% SDS-PAGE analysis of 3µg ab99520.

文献

ab99520 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab99520.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册