Recombinant人DAP Kinase 1 protein (ab63191)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • 种属Human
    • 氨基酸1 to 363

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技术指标

Our Abpromise guarantee covers the use of ab63191 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Specific activity: 49 nmol/min/mg.
  • 应用

    Functional Studies

    SDS-PAGE

  • 形式Liquid
  • 补充说明

    ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • DAK1
    • DAP K1
    • DAP kinase 1
    • DAPK
    • DAPK 1
    • DAPK1
    • DAPK1_HUMAN
    • Death Associated Protein Kinase 1
    • Death-associated protein kinase 1
    • DKFZp781I035
    see all
  • 功能Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis.
  • 序列相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
    Contains 10 ANK repeats.
    Contains 1 death domain.
    Contains 1 protein kinase domain.
  • 翻译后修饰Ubiquitinated by the BCR(KLHL20) E3 ubiquitin ligase complex, leading to its degradation by the proteasome.
  • 细胞定位Cytoplasm. Colocalizes with the actin filament system.
  • Information by UniProt

Recombinant human DAP Kinase 1 protein 图像

  • Sample Kinase Activity Plot.
  • ab63191 on SDS-PAGE. Molecular Weight: ~71 kDa.

Recombinant human DAP Kinase 1 protein (ab63191)参考文献

ab63191 has not yet been referenced specifically in any publications.

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