Recombinant人Cytokeratin 3 protein (ab114414)

概述

  • 产品名称Recombinant人Cytokeratin 3 protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP12035
    • 种属Human
    • 序列LLQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMED LVEDFKKK
    • 分子量32 kDa including tags
    • 氨基酸232 to 289

技术指标

Our Abpromise guarantee covers the use of ab114414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    ELISA

    SDS-PAGE

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • 65 kDa cytokeratin
    • CK-3
    • CK3
    • Cytokeratin-3
    • K2C3_HUMAN
    • K3
    • Keratin
    • Keratin 3
    • Keratin type II cytoskeletal 3
    • Keratin-3
    • KRT3
    • type II cytoskeletal 3
    • Type-II keratin Kb3
    see all
  • 组织特异性Cornea specific.
  • 疾病相关Defects in KRT3 are a cause of Meesmann corneal dystrophy (MECD) [MIM:122100]; also abbreviated as MCD and known as juvenile epithelial corneal dystrophy of Meesmann. MECD is an autosomal dominant disease that causes fragility of the anterior corneal epithelium. Patients are usually asymptomatic until adulthood when rupture of the corneal microcysts may cause erosions, producing clinical symptoms such as photophobia, contact lens intolerance and intermittent diminution of visual acuity. Rarely, subepithelial scarring causes irregular corneal astigmatism and permanent visual impairment. Histological examination shows a disorganized and thickened epithelium with widespread cytoplasmic vacuolation and numerous small, round, debris-laden intraepithelial cysts.
  • 序列相似性Belongs to the intermediate filament family.
  • Information by UniProt

Recombinant Human Cytokeratin 3 protein 图像

  • 12.5% SDS-PAGE stained with Coomassie Blue.

Recombinant Human Cytokeratin 3 protein (ab114414)参考文献

ab114414 has not yet been referenced specifically in any publications.

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