Recombinant人Cytokeratin 13 protein (ab112315)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVS CGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLL TGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPER DYSPYYKTIEELRDKILTATIENNRVILEIDNARLAVDDFRLKYENELAL RQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEF SNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKS AELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVA ETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQ EIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASGR RTSDVRRP
    • 分子量
      76 kDa including tags
    • 氨基酸
      1 to 458
    • 标签
      GST tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab112315 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

    ELISA

  • 形式
    Liquid
  • 补充说明
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione

常规信息

  • 别名
    • 47 kDa cytokeratin
    • CK-13
    • CK13
    • Cytokeratin 13
    • Cytokeratin-13
    • K13
    • K1C13_HUMAN
    • Ka13
    • Keratin
    • Keratin 13
    • keratin type I cytoskeletal 13
    • Keratin-13
    • Krt-1.13
    • Krt1-13
    • KRT13
    • MGC161462
    • MGC3781
    • type I cytoskeletal 13
    • Type I keratin Ka13
    • WSN2
    see all
  • 组织特异性
    Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.
  • 疾病相关
    Defects in KRT13 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.
  • 序列相似性
    Belongs to the intermediate filament family.
  • 翻译后修饰
    O-glycosylated; glycans consist of single N-acetylglucosamine residues.
  • Information by UniProt

图片

  • ab112315 on a 12.5% SDS-PAGE stained with coomassie blue

文献

ab112315 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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