Recombinant人Cytochrome P450 2A6 protein (ab114776)

概述

  • 产品名称
    Recombinant人Cytochrome P450 2A6 protein
  • 蛋白长度
    Protein fragment

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      LGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGL ARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVGFATIPRNYTMSFLPR
    • 分子量
      37 kDa including tags
    • 氨基酸
      395 to 494

技术指标

Our Abpromise guarantee covers the use of ab114776 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    Western blot

    SDS-PAGE

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Coumarin 7 hydroxylase
    • Coumarin 7-hydroxylase
    • CP2A6_HUMAN
    • CPA6
    • CYP2A
    • CYP2A3
    • CYP2A6
    • CYPIIA6
    • Cytochrome P450 2A6
    • Cytochrome P450 IIA3
    • Cytochrome P450 subfamily IIA (phenobarbital inducible) polypeptide 6
    • Cytochrome P450(I)
    • Cytochrome P450, family 2 subfamily A polypeptide 6
    • Flavoprotein linked monooxygenase
    • P450C2A
    • P450PB
    • Xenobiotic monooxygenase
    see all
  • 功能
    Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Possesses low phenacetin O-deethylation activity.
  • 组织特异性
    Liver.
  • 序列相似性
    Belongs to the cytochrome P450 family.
  • 细胞定位
    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt

图片

  • ab114776 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

文献

ab114776 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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